Microbiology, infectious diseasesby

Clinical Chemistry and Laboratory Medicine (CCLM)

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Year
2015
DOI
10.1515/cclm-2015-5033
Subject
Clinical Biochemistry / Biochemistry, medical

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Microbiology, infectious diseases

W249

HEPATITIS B VIRUS - KNOWLEDGE, ATTITUDE AND PRACTICES AMONG TAXI DRIVERS IN CAPE COAST METROPOLIS

S.M. Adamu1 1University of Cape Coast, School of Medical School, Cape Coast

BACKGROUND-AIM

The treat posed by hepatitis B virus (HBV) continues to assume alarming proportions in areas of public health and national development. Globally 2 billion people have been infected with HBV at some point in time in their life time and 360 to 400 million people which represents about 5% of the world’s population are chronic carriers. An estimated 600,000 deaths occur annually due to consequences/complications of HBV. The aim of this study was (i) to assess the knowledge of taxi drivers and relating this knowledge to attitudes and practices by the drivers and (ii) to determine the prevalence of HBV among the taxi drivers in Cape Coast metropolis.

METHODS

A cross sectional study was undertaken with 150 taxi drivers all in Cape Coast metropolis between 5th September to 24th December 2012 using a designed questionnaire. In addition about 5 ml of blood sample was withdrawn into plain tubes for serum separation for HBV serology test.

RESULTS 102 respondents (68%) had heard about HBV but only 26% knew about the causes and mode of transmission of the infection. Practices such as alcohol intake (54.7%), having multiple sexual partners or patronizing commercial sex workers (5.3%), non-condom use (72%) and use of herbal medication (68.8%) were very significant factors that increased their risk for infection and progression of HBV infection. The prevalence of the infection among the drivers was 7.0%. Most of the drivers were also not sure of how they would respond to an infected person. There is thus the need for a larger study to ascertain the extent of HBV in the metropolis and comprehensive health education campaigns on mode of transmission and prevention strategies within the community and in the mass media.

CONCLUSION

The was a very high level of knowledge as per having heard of the disease but very low knowledge on the causes, mode of transmission and prevention strategies.

The prevalence rate of 7.0% was recorded for the study

Poster Abstracts – EuroMedLab Paris 2015 – Paris, 21-25 June 2015 • DOI 10.1515/cclm-2015-5033

Clin Chem Lab Med 2015; 53, Special Suppl, pp S1 – S1450, June 2015 • Copyright © by Walter de Gruyter • Berlin • Boston S1273

Microbiology, infectious diseases

W250

RAOULTELLA ORNITHINOLYTICA – A HUMAN INFECTION CASE REPORT

S. Paulo1, F. Carrega2, L. Porto2, A. Gama2, P. Amantegui1, S. Almeida1, M.C. Faria1 1Department of Clinical Pathology, Centro Hospitalar da Cova da Beira, Covilhã, Portugal 2Department of Internal Medicine, Centro Hospitalar da Cova da Beira, Covilhã, Portugal

BACKGROUND-AIM

Raoultella ornithinolytica was first described in 1989 by Sakazaki et al. This bacterium is a gram-negative encapsulated aerobic bacillus belonging to family Enterobacteriaceae that is found in aquatic environments. It has the ability to convert histidine to histamine so the infection with this microorganism causes lesions of redness and flushing of the skin. There are only a few reports of human infection by R. ornithinolytica in the literature.

METHODS

A 33-year-old caucasian male came to our ER due to extensive edema and redness in the left hand after trauma, also presenting fever (38,6ºC). The patient’s medical history is very important because he is haemophilic, hepatitis C positive and has a drug addiction background. The CT scan showed difused edema of the subcutaneous cellular tissue without signs of fracture or necrosis.

RESULTS

The collection of a sample of pus, cultures and then identification with Vitek 2 System ( BioMérieux, France), made possible to isolate Raoutella ornythinolytica resistant to Ampicillin and sensible to Amoxicillin + Clavulanic acid, Cefuroxime, Gentamicin and Ciprofloxacin.Flucloxacillin empirical antimicrobial therapy was then switched to amoxicilin + clavulanic acid for 13 days. After the patient presented a new episode of fever we made new cultures that provided the isolation of Enterobacter cloacae sp resistant to Ampicillin, Amoxicillin + Clavulanic acid and sensible to

Cefuroxime, Gentamicin and Ciprofloxacin.There was a good clinical evolution with antibiotic treatment and local care of the lesion, and his analytical status significantly improved: white blood cell count of 7,7×10 9/L, hemoglobin of 12,6 g/dL, platelet count of 226000×10 9/L, serum sodium of 142 mEq/L, potassium of 5.3 mEq/L, urea of 40 mEq/L, and creatinine of 0,61 mg/dL. C-reactive protein levels were 0,76 mg/L.

CONCLUSION

This case emphasizes the importance of a good clinical interrogation, with extensive epidemiological questions. This patient denied all our questions regarding actual drug abuse but we consider possible that he may continue this habits possible using contaminated water.

Poster Abstracts – EuroMedLab Paris 2015 – Paris, 21-25 June 2015 • DOI 10.1515/cclm-2015-5033

Clin Chem Lab Med 2015; 53, Special Suppl, pp S1 – S1450, June 2015 • Copyright © by Walter de Gruyter • Berlin • Boston S1274

Microbiology, infectious diseases

W251

HEMATOLOGICAL CHANGES IN PATIENTS WITH ACUTE MALARIA IMPORTED TO ALBANIA

M. Kokici3, N. Como1, A. Harxhi1, D. Kraja2, A. Pilaca1, P. Pipero1, E. Ramosaco1, E. Ramosaco1, K. Shkurti-leka1, F. Kokici4 1Infectious Diseases Service, 'Mother Theresa Hospital', Tirana, Albania 2Infectious Diseases Service, 'Mother Theresa' Hospital, Tirana, Albania 3Laboratory Service, 'Mother Theresa Hospital', Tirana, Albania 4University Hospital ‘Shefqet Ndroqi’, Tirana, Albania

BACKGROUND-AIM

Determination and evaluation of pameters of the hemogram of patients with acute Malaria.

METHODS

We studied 35 Albanian patients, 18-45 years, diagnosed with acute Malaria in the Infectious Diseases Service at the

University Hospital Center "Mother Teresa", Tirana during the period May 2010-December 2014. To all patients it was taken venous blood (with EDTA) for the hemogram, and blood in the finger for the thick and thin film. Blood in EDTA was measured in cell counter Sysmex, while for the realization of the thin film, the standard protocol was implemented.